Detection, isolation and characterization of principle synthetic route indicative impurity in telmisartan

Detection, isolation and characterization of principle synthetic route indicative impurity in telmisartan

An unknown impurity was detected in the telmisartan bulk drug (active pharmaceutical ingredient – API) using an isocratic reversed-phase high performance liquid chromatography (HPLC). This impurity was isolated by preparative HPLC. Spectral data of the isolated impurity were collected. Based on the...

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Bibliographic Details
Main Authors: V. Srinivasan, H. Sivaramakrishnan, B. Karthikeyan
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:Arabian Journal of Chemistry
Subjects:
Telmisartan
Impurity
Characterization
HPLC
MS
NMR
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535212000688

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