Targeting E-Selectin to Tackle Cancer Using Uproleselan

E-selectin is a vascular adhesion molecule expressed mainly on endothelium, and its primary role is to facilitate leukocyte cell trafficking by recognizing ligand surface proteins. E-selectin gained a new role since it was demonstrated to be involved in cancer cell trafficking, stem-like properties...

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Bibliographic Details
Main Authors: Barbara Muz, Anas Abdelghafer, Matea Markovic, Jessica Yavner, Anupama Melam, Noha Nabil Salama, Abdel Kareem Azab
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/2/335