Ion Association Methods for the Determination of Fexofenadine in Pharmaceutical Preparations

Ion Association Methods for the Determination of Fexofenadine in Pharmaceutical Preparations

Two simple and sensitive Visible spectrophotometric methods (A and B) for the determination of Fexofenadine (FEX) in bulk sample and pharmaceutical formulations are described. Methods A and B are based on the formation of ion-association complex involving carboxylic acid group of FEX and the basic...

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Main Authors: L. D. Srinivas, P. Ravi Kumar, B. S. Sastry
Format: Article
Language:English
Published: Hindawi Limited 2005-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2005/370478
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spelling doaj-0f10d1558a774bd7a1acbeb1d14b80832020-11-25T00:31:51ZengHindawi LimitedE-Journal of Chemistry0973-49452090-98102005-01-012319920210.1155/2005/370478Ion Association Methods for the Determination of Fexofenadine in Pharmaceutical PreparationsL. D. Srinivas0P. Ravi Kumar1B. S. Sastry2University College of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003, IndiaUniversity College of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003, IndiaUniversity College of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003, IndiaTwo simple and sensitive Visible spectrophotometric methods (A and B) for the determination of Fexofenadine (FEX) in bulk sample and pharmaceutical formulations are described. Methods A and B are based on the formation of ion-association complex involving carboxylic acid group of FEX and the basic dyes, Safranin-O (SFN-O, method A), methylene blue (MB, method B). The results obtained in the above two methods are reproducible and are statistically validated and found to be suitable for the assay of Fexofenadine in bulk and its pharmaceutical formulations.http://dx.doi.org/10.1155/2005/370478
collection DOAJ
language English
format Article
sources DOAJ
author L. D. Srinivas
P. Ravi Kumar
B. S. Sastry
spellingShingle L. D. Srinivas
P. Ravi Kumar
B. S. Sastry
Ion Association Methods for the Determination of Fexofenadine in Pharmaceutical Preparations
E-Journal of Chemistry
author_facet L. D. Srinivas
P. Ravi Kumar
B. S. Sastry
author_sort L. D. Srinivas
title Ion Association Methods for the Determination of Fexofenadine in Pharmaceutical Preparations
title_short Ion Association Methods for the Determination of Fexofenadine in Pharmaceutical Preparations
title_full Ion Association Methods for the Determination of Fexofenadine in Pharmaceutical Preparations
title_fullStr Ion Association Methods for the Determination of Fexofenadine in Pharmaceutical Preparations
title_full_unstemmed Ion Association Methods for the Determination of Fexofenadine in Pharmaceutical Preparations
title_sort ion association methods for the determination of fexofenadine in pharmaceutical preparations
publisher Hindawi Limited
series E-Journal of Chemistry
issn 0973-4945
2090-9810
publishDate 2005-01-01
description Two simple and sensitive Visible spectrophotometric methods (A and B) for the determination of Fexofenadine (FEX) in bulk sample and pharmaceutical formulations are described. Methods A and B are based on the formation of ion-association complex involving carboxylic acid group of FEX and the basic dyes, Safranin-O (SFN-O, method A), methylene blue (MB, method B). The results obtained in the above two methods are reproducible and are statistically validated and found to be suitable for the assay of Fexofenadine in bulk and its pharmaceutical formulations.
url http://dx.doi.org/10.1155/2005/370478
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AT pravikumar ionassociationmethodsforthedeterminationoffexofenadineinpharmaceuticalpreparations
AT bssastry ionassociationmethodsforthedeterminationoffexofenadineinpharmaceuticalpreparations
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