Ozone Enhances Diesel Exhaust Particles (DEP)-Induced Interleukin-8 (IL-8) Gene Expression in Human Airway Epithelial Cells through Activation of Nuclear Factors- κB (NF-κB) and IL-6 (NF-IL6)

Ozone Enhances Diesel Exhaust Particles (DEP)-Induced Interleukin-8 (IL-8) Gene Expression in Human Airway Epithelial Cells through Activation of Nuclear Factors- κB (NF-κB) and IL-6 (NF-IL6)

Ozone, a highly reactive oxidant gas is a major component of photochemical smog. As an inhaled toxicant, ozone induces its adverse effects mainly on the lung. Inhalation of particulate matter has been reported to cause airway inflammation in humans and animals. Furthermore, epidemiological evidence...

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Bibliographic Details
Main Authors: James Kelley, Ramzi M. Kafoury
Format: Article
Language:English
Published: MDPI AG 2005-12-01
Series:International Journal of Environmental Research and Public Health
Subjects:
Ozone
diesel exhaust particles
lung inflammation
interleukin-8
airway epithelial cells
transcription factors
Online Access:http://www.mdpi.com/1660-4601/2/3/403/

Internet

http://www.mdpi.com/1660-4601/2/3/403/

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