N<sup>6</sup>-Adenosine Methylation in RNA and a Reduced m<sub>3</sub>G/TMG Level in Non-Coding RNAs Appear at Microirradiation-Induced DNA Lesions

N<sup>6</sup>-Adenosine Methylation in RNA and a Reduced m<sub>3</sub>G/TMG Level in Non-Coding RNAs Appear at Microirradiation-Induced DNA Lesions

The DNA damage response is mediated by both DNA repair proteins and epigenetic markers. Here, we observe that N<sup>6</sup>-methyladenosine (m<sup>6</sup>A), a mark of the epitranscriptome, was common in RNAs accumulated at UV-damaged chromatin; however, inhibitors of RNA pol...

Full description

Bibliographic Details
Main Authors: Alena Svobodová Kovaříková, Lenka Stixová, Aleš Kovařík, Denisa Komůrková, Soňa Legartová, Paolo Fagherazzi, Eva Bártová
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
dna repair
rna methylation
mettl-like enzymes
histones
epigenetics
Online Access:https://www.mdpi.com/2073-4409/9/2/360

Internet

https://www.mdpi.com/2073-4409/9/2/360

Similar Items