Evolution of Proteins and Proteomes: A Phylogenetics Approach

Evolution of Proteins and Proteomes: A Phylogenetics Approach

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The study of evolutionary relationships among protein sequences was one of the first applications of bioinformatics. Since then, and accompanying the wealth of biological data produced by genome sequencing and other high-throughput techniques, the use of bioinformatics in general and phylogenetics i...

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Main Author: Toni Gabaldón
Format: Article
Language:English
Published: SAGE Publishing 2005-01-01
Series:Evolutionary Bioinformatics
Online Access:https://doi.org/10.1177/117693430500100004
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spelling doaj-0f04ce3a4a12460ab8224288c5a8bf5b2020-11-25T03:00:58ZengSAGE PublishingEvolutionary Bioinformatics1176-93432005-01-01110.1177/117693430500100004Evolution of Proteins and Proteomes: A Phylogenetics ApproachToni Gabaldón0Bioinformatics Department, Centro de Investigación Principe FelipeThe study of evolutionary relationships among protein sequences was one of the first applications of bioinformatics. Since then, and accompanying the wealth of biological data produced by genome sequencing and other high-throughput techniques, the use of bioinformatics in general and phylogenetics in particular has been gaining ground in the study of protein and proteome evolution. Nowadays, the use of phylogenetics is instrumental not only to infer the evolutionary relationships among species and their genome sequences, but also to reconstruct ancestral states of proteins and proteomes and hence trace the paths followed by evolution. Here I survey recent progress in the elucidation of mechanisms of protein and proteome evolution in which phylogenetics has played a determinant role.https://doi.org/10.1177/117693430500100004
collection DOAJ
language English
format Article
sources DOAJ
author Toni Gabaldón
spellingShingle Toni Gabaldón
Evolution of Proteins and Proteomes: A Phylogenetics Approach
Evolutionary Bioinformatics
author_facet Toni Gabaldón
author_sort Toni Gabaldón
title Evolution of Proteins and Proteomes: A Phylogenetics Approach
title_short Evolution of Proteins and Proteomes: A Phylogenetics Approach
title_full Evolution of Proteins and Proteomes: A Phylogenetics Approach
title_fullStr Evolution of Proteins and Proteomes: A Phylogenetics Approach
title_full_unstemmed Evolution of Proteins and Proteomes: A Phylogenetics Approach
title_sort evolution of proteins and proteomes: a phylogenetics approach
publisher SAGE Publishing
series Evolutionary Bioinformatics
issn 1176-9343
publishDate 2005-01-01
description The study of evolutionary relationships among protein sequences was one of the first applications of bioinformatics. Since then, and accompanying the wealth of biological data produced by genome sequencing and other high-throughput techniques, the use of bioinformatics in general and phylogenetics in particular has been gaining ground in the study of protein and proteome evolution. Nowadays, the use of phylogenetics is instrumental not only to infer the evolutionary relationships among species and their genome sequences, but also to reconstruct ancestral states of proteins and proteomes and hence trace the paths followed by evolution. Here I survey recent progress in the elucidation of mechanisms of protein and proteome evolution in which phylogenetics has played a determinant role.
url https://doi.org/10.1177/117693430500100004
work_keys_str_mv AT tonigabaldon evolutionofproteinsandproteomesaphylogeneticsapproach
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