High serotonin levels during brain development alter the structural input-output connectivity of neural networks in the rat somatosensory layer IV

High serotonin levels during brain development alter the structural input-output connectivity of neural networks in the rat somatosensory layer IV

Homeostatic regulation of serotonin (5-HT) concentration is critical for normal topographical organization and development of thalamocortical (TC) afferent circuits. Down-regulation of the serotonin transporter (SERT) and the consequent impaired reuptake of 5-HT at the synapse, results in a reduced...

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Bibliographic Details
Main Authors: Stéphanie eMiceli, Moritz eNegwer, Fenneke evan Eijs, Carla eKalkhoven, Ilja evan Lierop, Judith eHomberg, Dirk eSchubert
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Electrophysiology
Pyramidal Cells
Serotonin
barrel cortex
morphology
serotonin transporter
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00088/full

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