Screening for toxic amyloid in yeast exemplifies the role of alternative pathway responsible for cytotoxicity.

The relationship between amyloid and toxic species is a central problem since the discovery of amyloid structures in different diseases. Despite intensive efforts in the field, the deleterious species remains unknown at the molecular level. This may reflect the lack of any structure-toxicity study b...

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Bibliographic Details
Main Authors: Julien Couthouis, Karine Rébora, Françoise Immel, Karine Berthelot, Michel Castroviejo, Christophe Cullin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19262694/pdf/?tool=EBI