An alternative food source for metabolism and longevity studies in Caenorhabditis elegans

An alternative food source for metabolism and longevity studies in Caenorhabditis elegans

Beydoun, Choi et al. develop a metabolically inactive food source for C. elegans worms that minimizes the confounding effects of bacterial metabolism on worm metabolism and aging. They find that worms eat and grow well on a paraformaldehyde (PFA)-treated E. coli food source, recommending the use of...

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Bibliographic Details
Main Authors: Safa Beydoun, Hyo Sub Choi, Gabrielle Dela-Cruz, Joseph Kruempel, Shijiao Huang, Daphne Bazopoulou, Hillary A. Miller, Megan L. Schaller, Charles R. Evans, Scott F. Leiser
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01764-4
Description
Summary:Beydoun, Choi et al. develop a metabolically inactive food source for C. elegans worms that minimizes the confounding effects of bacterial metabolism on worm metabolism and aging. They find that worms eat and grow well on a paraformaldehyde (PFA)-treated E. coli food source, recommending the use of 0.5% PFA-killed bacteria as a nematode food source for metabolic experiments.
ISSN:2399-3642

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