Low WT1 transcript levels at diagnosis predicted poor outcomes of acute myeloid leukemia patients with t(8;21) who received chemotherapy or allogeneic hematopoietic stem cell transplantation

Low WT1 transcript levels at diagnosis predicted poor outcomes of acute myeloid leukemia patients with t(8;21) who received chemotherapy or allogeneic hematopoietic stem cell transplantation

Abstract Background Acute myeloid leukemia (AML) with t(8;21) is a heterogeneous disease. Identifying AML patients with t(8;21) who have a poor prognosis despite achieving remission is important for determining the best subsequent therapy. This study aimed to evaluate the impact of Wilm tumor gene-1...

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Bibliographic Details
Main Authors: Ya-Zhen Qin, Yu Wang, Hong-Hu Zhu, Robert Peter Gale, Mei-Jie Zhang, Qian Jiang, Hao Jiang, Lan-Ping Xu, Huan Chen, Xiao-Hui Zhang, Yan-Rong Liu, Yue-Yun Lai, Bin Jiang, Kai-Yan Liu, Xiao-Jun Huang
Format: Article
Language:English
Published: BMC 2016-05-01
Series:Chinese Journal of Cancer
Subjects:
Acute myeloid leukemia
RUNX1-RUNX1T1 transcript level
WT1 transcript level
C-KIT mutation
Allogeneic hematopoietic stem cell transplantation
Online Access:http://link.springer.com/article/10.1186/s40880-016-0110-6

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