What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists?
Lu et al.1 previously demonstrated that antagonist antibodies against the GIP receptor promote weight loss combined with GLP-1. They now elegantly developed a conjugate of GIPR antibodies and GLP-1 and show effective weight loss in obese non-human primates.
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| Format: | Article |
| Language: | English |
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Elsevier
2021-05-01
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| Series: | Cell Reports Medicine |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666379121001129 |
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doaj-0ecbcb53b04a4747a1f9bde12f3726442021-05-20T07:53:14ZengElsevierCell Reports Medicine2666-37912021-05-0125100284What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists?Jens Juul Holst0NovoNordisk Foundation Center for Basic Metabolic Research and Department of Biomedical Sciences, The Panum Institute, University of Copenhagen, Denmark; Corresponding authorLu et al.1 previously demonstrated that antagonist antibodies against the GIP receptor promote weight loss combined with GLP-1. They now elegantly developed a conjugate of GIPR antibodies and GLP-1 and show effective weight loss in obese non-human primates.http://www.sciencedirect.com/science/article/pii/S2666379121001129 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Jens Juul Holst |
| spellingShingle |
Jens Juul Holst What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists? Cell Reports Medicine |
| author_facet |
Jens Juul Holst |
| author_sort |
Jens Juul Holst |
| title |
What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists? |
| title_short |
What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists? |
| title_full |
What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists? |
| title_fullStr |
What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists? |
| title_full_unstemmed |
What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists? |
| title_sort |
what combines best with glp-1 for obesity treatment: gip receptor agonists or antagonists? |
| publisher |
Elsevier |
| series |
Cell Reports Medicine |
| issn |
2666-3791 |
| publishDate |
2021-05-01 |
| description |
Lu et al.1 previously demonstrated that antagonist antibodies against the GIP receptor promote weight loss combined with GLP-1. They now elegantly developed a conjugate of GIPR antibodies and GLP-1 and show effective weight loss in obese non-human primates. |
| url |
http://www.sciencedirect.com/science/article/pii/S2666379121001129 |
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