What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists?
Lu et al.1 previously demonstrated that antagonist antibodies against the GIP receptor promote weight loss combined with GLP-1. They now elegantly developed a conjugate of GIPR antibodies and GLP-1 and show effective weight loss in obese non-human primates.
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| Format: | Article |
| Language: | English |
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Elsevier
2021-05-01
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| Series: | Cell Reports Medicine |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666379121001129 |
| Summary: | Lu et al.1 previously demonstrated that antagonist antibodies against the GIP receptor promote weight loss combined with GLP-1. They now elegantly developed a conjugate of GIPR antibodies and GLP-1 and show effective weight loss in obese non-human primates. |
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| ISSN: | 2666-3791 |