Breakdown of Phosphatidylserine Asymmetry Following Treatment of Erythrocytes with Lumefantrine

Breakdown of Phosphatidylserine Asymmetry Following Treatment of Erythrocytes with Lumefantrine

Background: Lumefantrine, a commonly used antimalarial drug, inhibits hemozoin formation in parasites. Several other antimalarial substances counteract parasitemia by triggering suicidal death or eryptosis of infected erythrocytes. Eryptosis is characterized by cell shrinkage and cell membrane scram...

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Bibliographic Details
Main Authors: Kousi Alzoubi, Bassel Alktifan, Gergely Oswald, Myriam Fezai, Majed Abed, Florian Lang
Format: Article
Language:English
Published: MDPI AG 2014-02-01
Series:Toxins
Subjects:
phosphatidylserine
lumefantrine
calcium
ceramide
cell volume
eryptosis
Online Access:http://www.mdpi.com/2072-6651/6/2/650

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http://www.mdpi.com/2072-6651/6/2/650

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