A celiac cellular phenotype, with altered LPP sub-cellular distribution, is inducible in controls by the toxic gliadin peptide P31-43.

A celiac cellular phenotype, with altered LPP sub-cellular distribution, is inducible in controls by the toxic gliadin peptide P31-43.

Celiac disease (CD) is a frequent inflammatory intestinal disease, with a genetic background, caused by gliadin-containing food. Undigested gliadin peptides P31-43 and P57-68 induce innate and adaptive T cell-mediated immune responses, respectively. Alterations in the cell shape and actin cytoskelet...

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Bibliographic Details
Main Authors: Merlin Nanayakkara, Roberta Kosova, Giuliana Lania, Marco Sarno, Alessandra Gaito, Martina Galatola, Luigi Greco, Marialaura Cuomo, Riccardo Troncone, Salvatore Auricchio, Renata Auricchio, Maria Vittoria Barone
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3838353?pdf=render

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