A Capillary-Perfused, Nanocalorimeter Platform for Thermometric Enzyme-Linked Immunosorbent Assay with Femtomole Sensitivity

A Capillary-Perfused, Nanocalorimeter Platform for Thermometric Enzyme-Linked Immunosorbent Assay with Femtomole Sensitivity

Enzyme-catalyzed chemical reactions produce heat. We developed an enclosed, capillary-perfused nanocalorimeter platform for thermometric enzyme-linked immunosorbent assay (TELISA). We used catalase as enzymes to model the thermal characteristics of the micromachined calorimeter. Model-assisted signa...

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Bibliographic Details
Main Authors:	Evan Kazura, Ray Mernaugh, Franz Baudenbacher
Format:	Article
Language:	English
Published:	MDPI AG 2020-06-01
Series:	Biosensors
Subjects:	microfabricated calorimeter ELISA thermometric ELISA biosensor model-assisted signal analysis
Online Access:	https://www.mdpi.com/2079-6374/10/6/71

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