The PPCD1 mouse: characterization of a mouse model for posterior polymorphous corneal dystrophy and identification of a candidate gene.

The PPCD1 mouse, a spontaneous mutant that arose in our mouse colony, is characterized by an enlarged anterior chamber resulting from metaplasia of the corneal endothelium and blockage of the iridocorneal angle by epithelialized corneal endothelial cells. The presence of stratified multilayered corn...

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Bibliographic Details
Main Authors: Anna L Shen, Kathleen A O'Leary, Richard R Dubielzig, Norman Drinkwater, Christopher J Murphy, Charles B Kasper, Christopher A Bradfield
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2922377?pdf=render