Natural Polymorphisms Conferring Resistance to HCV Protease and Polymerase Inhibitors in Treatment-Naïve HIV/HCV Co-Infected Patients in China.

<h4>Background</h4>The advent of direct-acting agents (DAAs) has improved treatment of HCV in HIV co-infection, but may be limited by primary drug resistance. This study reports the prevalence of natural polymorphisms conferring resistance to NS3/4A protease inhibitors and NS5B polymeras...

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Bibliographic Details
Main Authors: Kali Zhou, Zhiwei Liang, Charles Wang, Fengyu Hu, Chuanyi Ning, Yun Lan, Xiaoping Tang, Joseph D Tucker, Weiping Cai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0157438