Differential genome-wide profiling of alternative polyadenylation sites in nasopharyngeal carcinoma by high-throughput sequencing

Differential genome-wide profiling of alternative polyadenylation sites in nasopharyngeal carcinoma by high-throughput sequencing

Abstract Background Alternative polyadenylation (APA) is a widespread phenomenon in the posttranscriptional regulation of gene expression that generates mRNAs with alternative 3′-untranslated regions (3’UTRs). APA contributes to the pathogenesis of various diseases, including cancer. However, the po...

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Bibliographic Details
Main Authors: Ya-Fei Xu, Ying-Qing Li, Na Liu, Qing-Mei He, Xin-Ran Tang, Xin Wen, Xiao-Jing Yang, Ying Sun, Jun Ma, Ling-Long Tang
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Journal of Biomedical Science
Subjects:
Alternative polyadenylation
Genome-wide profiling
High-throughput sequencing
Nasopharyngeal carcinoma
Online Access:http://link.springer.com/article/10.1186/s12929-018-0477-6

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