Statistical design of personalized medicine interventions: The Clarification of Optimal Anticoagulation through Genetics (COAG) trial

<p>Abstract</p> <p>Background</p> <p>There is currently much interest in pharmacogenetics: determining variation in genes that regulate drug effects, with a particular emphasis on improving drug safety and efficacy. The ability to determine such variation motivates the...

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Bibliographic Details
Main Authors: Gage Brian F, Anderson Jeffrey L, Rosenberg Yves, Kimmel Stephen E, Geller Nancy L, Joo Jungnam, French Benjamin, Johnson Julie A, Ellenberg Jonas H
Format: Article
Language:English
Published: BMC 2010-11-01
Series:Trials
Online Access:http://www.trialsjournal.com/content/11/1/108