The cytolethal distending toxin contributes to microbial virulence and disease pathogenesis by acting as a tri-perditious toxin

The cytolethal distending toxin contributes to microbial virulence and disease pathogenesis by acting as a tri-perditious toxin

This review summarizes the current status and recent advances in our understanding of the role that the cytolethal distending toxin (Cdt) plays as a virulence factor in promoting disease by toxin-producing pathogens. A major focus of this review is on the relationship between structure and function...

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Bibliographic Details
Main Authors: Monika D Scuron, Kathleen Boesze-Battaglia, Mensur Dlakic, Bruce J Shenker
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Apoptosis
Cell Cycle
Epithelial Cells
Immune System
Inflammation
Lymphocytes
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00168/full

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