Fast Fluorine-18 labeling and preclinical evaluation of novel Mucin1 and its Folate hybrid peptide conjugate for targeting breast carcinoma

Fast Fluorine-18 labeling and preclinical evaluation of novel Mucin1 and its Folate hybrid peptide conjugate for targeting breast carcinoma

Abstract Background There is a need to develop new and more potent radiofluorinated peptide and their hybrid conjugates for multiple-receptors targeting properties that overexpress on many cancers. Methods We have synthesized MUC1-[18F] SFB and MUC1-FA-[18F] SFB hybrid conjugates using a convenient...

Full description

Bibliographic Details
Main Authors: I. Al Jammaz, B. Al-Otaibi, Y. Al-Malki, A. Abousekhrah, S. M. Okarvi
Format: Article
Language:English
Published: SpringerOpen 2021-03-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
18F-fluorination
18F-fluoromucin 1
18F-fluorofolate
Hybrid-peptide
Breast cancer
Online Access:https://doi.org/10.1186/s41181-021-00127-y

Similar Items

Similar Items