Suppression of peroxiredoxin 4 in glioblastoma cells increases apoptosis and reduces tumor growth.

Suppression of peroxiredoxin 4 in glioblastoma cells increases apoptosis and reduces tumor growth.

Glioblastoma multiforme (GBM), the most common and aggressive primary brain malignancy, is incurable despite the best combination of current cancer therapies. For the development of more effective therapies, discovery of novel candidate tumor drivers is urgently needed. Here, we report that peroxire...

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Bibliographic Details
Main Authors: Tae Hyong Kim, Jieun Song, Sheila R Alcantara Llaguno, Eric Murnan, Sandya Liyanarachchi, Kamalakannan Palanichamy, Ji-Yeun Yi, Mariano Sebastian Viapiano, Ichiro Nakano, Sung Ok Yoon, Hong Wu, Luis F Parada, Chang-Hyuk Kwon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3419743?pdf=render

Internet

http://europepmc.org/articles/PMC3419743?pdf=render

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