ER-mitochondria contacts promote mtDNA nucleoids active transportation via mitochondrial dynamic tubulation

Mitochondrial DNA is found in nucleoids, which are distributed throughout the mitochondrial network and are thought to be passively distributed. Here, the authors show that mitochondrial dynamic tubulation at ER-mitochondria contact sites actively transports nucleoids.

Bibliographic Details
Main Authors: Jinshan Qin, Yuting Guo, Boxin Xue, Peng Shi, Yang Chen, Qian Peter Su, Huiwen Hao, Shujuan Zhao, Congying Wu, Li Yu, Dong Li, Yujie Sun
Format: Article
Language:English
Published: Nature Publishing Group 2020-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18202-4