Transfer Learning for an Automated Detection System of Fractures in Patients with Maxillofacial Trauma

An original maxillofacial fracture detection system (MFDS), based on convolutional neural networks and transfer learning, is proposed to detect traumatic fractures in patients. A convolutional neural network pre-trained on non-medical images was re-trained and fine-tuned using computed tomography (C...

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Main Authors: Maria Amodeo, Vincenzo Abbate, Pasquale Arpaia, Renato Cuocolo, Giovanni Dell’Aversana Orabona, Monica Murero, Marco Parvis, Roberto Prevete, Lorenzo Ugga
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/11/14/6293
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spelling doaj-0e68d34c123047828d1e3fb6ad72250a2021-07-23T13:29:09ZengMDPI AGApplied Sciences2076-34172021-07-01116293629310.3390/app11146293Transfer Learning for an Automated Detection System of Fractures in Patients with Maxillofacial TraumaMaria Amodeo0Vincenzo Abbate1Pasquale Arpaia2Renato Cuocolo3Giovanni Dell’Aversana Orabona4Monica Murero5Marco Parvis6Roberto Prevete7Lorenzo Ugga8Department of Electronics and Telecommunications (DET), Polytechnic University of Turin, 10129 Turin, ItalyDepartment of Neurosciences, Reproductive and Odontostomatological Science, University of Naples Federico II, 80131 Naples, ItalyInterdepartmental Research Center on Management and Innovation in Healthcare—CIRMIS, University of Naples Federico II, Via Pansini 5, 80138 Naples, ItalyInterdepartmental Research Center on Management and Innovation in Healthcare—CIRMIS, University of Naples Federico II, Via Pansini 5, 80138 Naples, ItalyDepartment of Neurosciences, Reproductive and Odontostomatological Science, University of Naples Federico II, 80131 Naples, ItalyDepartment of Social Sciences, University of Naples Federico II, 80131 Naples, ItalyDepartment of Electronics and Telecommunications (DET), Polytechnic University of Turin, 10129 Turin, ItalyDepartment of Electrical Engineering and Information Technology (DIETI), University of Naples Federico II, 80100 Naples, ItalyDepartment of Advanced Biomedical Sciences, University of Naples Federico II, 80131 Naples, ItalyAn original maxillofacial fracture detection system (MFDS), based on convolutional neural networks and transfer learning, is proposed to detect traumatic fractures in patients. A convolutional neural network pre-trained on non-medical images was re-trained and fine-tuned using computed tomography (CT) scans to produce a model for the classification of future CTs as either “fracture” or “noFracture”. The model was trained on a total of 148 CTs (120 patients labeled with “fracture” and 28 patients labeled with “noFracture”). The validation dataset, used for statistical analysis, was characterized by 30 patients (5 with “noFracture” and 25 with “fracture”). An additional 30 CT scans, comprising 25 “fracture” and 5 “noFracture” images, were used as the test dataset for final testing. Tests were carried out both by considering the single slices and by grouping the slices for patients. A patient was categorized as fractured if two consecutive slices were classified with a fracture probability higher than 0.99. The patients’ results show that the model accuracy in classifying the maxillofacial fractures is 80%. Even if the MFDS model cannot replace the radiologist’s work, it can provide valuable assistive support, reducing the risk of human error, preventing patient harm by minimizing diagnostic delays, and reducing the incongruous burden of hospitalization.https://www.mdpi.com/2076-3417/11/14/6293convolutional neural networktransfer learningmaxillofacial fracturescomputed tomography imagesradiography
collection DOAJ
language English
format Article
sources DOAJ
author Maria Amodeo
Vincenzo Abbate
Pasquale Arpaia
Renato Cuocolo
Giovanni Dell’Aversana Orabona
Monica Murero
Marco Parvis
Roberto Prevete
Lorenzo Ugga
spellingShingle Maria Amodeo
Vincenzo Abbate
Pasquale Arpaia
Renato Cuocolo
Giovanni Dell’Aversana Orabona
Monica Murero
Marco Parvis
Roberto Prevete
Lorenzo Ugga
Transfer Learning for an Automated Detection System of Fractures in Patients with Maxillofacial Trauma
Applied Sciences
convolutional neural network
transfer learning
maxillofacial fractures
computed tomography images
radiography
author_facet Maria Amodeo
Vincenzo Abbate
Pasquale Arpaia
Renato Cuocolo
Giovanni Dell’Aversana Orabona
Monica Murero
Marco Parvis
Roberto Prevete
Lorenzo Ugga
author_sort Maria Amodeo
title Transfer Learning for an Automated Detection System of Fractures in Patients with Maxillofacial Trauma
title_short Transfer Learning for an Automated Detection System of Fractures in Patients with Maxillofacial Trauma
title_full Transfer Learning for an Automated Detection System of Fractures in Patients with Maxillofacial Trauma
title_fullStr Transfer Learning for an Automated Detection System of Fractures in Patients with Maxillofacial Trauma
title_full_unstemmed Transfer Learning for an Automated Detection System of Fractures in Patients with Maxillofacial Trauma
title_sort transfer learning for an automated detection system of fractures in patients with maxillofacial trauma
publisher MDPI AG
series Applied Sciences
issn 2076-3417
publishDate 2021-07-01
description An original maxillofacial fracture detection system (MFDS), based on convolutional neural networks and transfer learning, is proposed to detect traumatic fractures in patients. A convolutional neural network pre-trained on non-medical images was re-trained and fine-tuned using computed tomography (CT) scans to produce a model for the classification of future CTs as either “fracture” or “noFracture”. The model was trained on a total of 148 CTs (120 patients labeled with “fracture” and 28 patients labeled with “noFracture”). The validation dataset, used for statistical analysis, was characterized by 30 patients (5 with “noFracture” and 25 with “fracture”). An additional 30 CT scans, comprising 25 “fracture” and 5 “noFracture” images, were used as the test dataset for final testing. Tests were carried out both by considering the single slices and by grouping the slices for patients. A patient was categorized as fractured if two consecutive slices were classified with a fracture probability higher than 0.99. The patients’ results show that the model accuracy in classifying the maxillofacial fractures is 80%. Even if the MFDS model cannot replace the radiologist’s work, it can provide valuable assistive support, reducing the risk of human error, preventing patient harm by minimizing diagnostic delays, and reducing the incongruous burden of hospitalization.
topic convolutional neural network
transfer learning
maxillofacial fractures
computed tomography images
radiography
url https://www.mdpi.com/2076-3417/11/14/6293
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