Which Gait Parameters and Walking Patterns Show the Significant Differences Between Parkinson’s Disease and Healthy Participants?

This study investigated the difference in the gait of patients with Parkinson’s disease (PD), age-matched controls and young controls during three walking patterns. Experiments were conducted with 24 PD, 24 age-matched controls and 24 young controls, and four gait intervals were measured u...

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Main Authors: Sana M Keloth, Rekha Viswanathan, Beth Jelfs, Sridhar Arjunan, Sanjay Raghav, Dinesh Kumar
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Biosensors
Subjects:
IMU
Online Access:https://www.mdpi.com/2079-6374/9/2/59
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spelling doaj-0e64af52ff1d4a2a93a525dece6e88012020-11-25T01:36:39ZengMDPI AGBiosensors2079-63742019-04-01925910.3390/bios9020059bios9020059Which Gait Parameters and Walking Patterns Show the Significant Differences Between Parkinson’s Disease and Healthy Participants?Sana M Keloth0Rekha Viswanathan1Beth Jelfs2Sridhar Arjunan3Sanjay Raghav4Dinesh Kumar5Biosignals Lab, School of Engineering, RMIT University, Melbourne, VIC 3000, AustraliaBiosignals Lab, School of Engineering, RMIT University, Melbourne, VIC 3000, AustraliaBiosignals Lab, School of Engineering, RMIT University, Melbourne, VIC 3000, AustraliaBiosignals Lab, School of Engineering, RMIT University, Melbourne, VIC 3000, AustraliaDandenong Neurology, Melbourne, VIC 3175, AustraliaBiosignals Lab, School of Engineering, RMIT University, Melbourne, VIC 3000, AustraliaThis study investigated the difference in the gait of patients with Parkinson’s disease (PD), age-matched controls and young controls during three walking patterns. Experiments were conducted with 24 PD, 24 age-matched controls and 24 young controls, and four gait intervals were measured using inertial measurement units (IMU). Group differences between the mean and variance of the gait parameters (stride interval, stance interval, swing interval and double support interval) for the three groups were calculated and statistical significance was tested. The results showed that the variance in each of the four gait parameters of PD patients was significantly higher compared with the controls, irrespective of the three walking patterns. This study showed that the variance of any of the gait interval parameters obtained using IMU during any of the walking patterns could be used to differentiate between the gait of PD and control people.https://www.mdpi.com/2079-6374/9/2/59Parkinson’s diseasegaitvarianceIMU
collection DOAJ
language English
format Article
sources DOAJ
author Sana M Keloth
Rekha Viswanathan
Beth Jelfs
Sridhar Arjunan
Sanjay Raghav
Dinesh Kumar
spellingShingle Sana M Keloth
Rekha Viswanathan
Beth Jelfs
Sridhar Arjunan
Sanjay Raghav
Dinesh Kumar
Which Gait Parameters and Walking Patterns Show the Significant Differences Between Parkinson’s Disease and Healthy Participants?
Biosensors
Parkinson’s disease
gait
variance
IMU
author_facet Sana M Keloth
Rekha Viswanathan
Beth Jelfs
Sridhar Arjunan
Sanjay Raghav
Dinesh Kumar
author_sort Sana M Keloth
title Which Gait Parameters and Walking Patterns Show the Significant Differences Between Parkinson’s Disease and Healthy Participants?
title_short Which Gait Parameters and Walking Patterns Show the Significant Differences Between Parkinson’s Disease and Healthy Participants?
title_full Which Gait Parameters and Walking Patterns Show the Significant Differences Between Parkinson’s Disease and Healthy Participants?
title_fullStr Which Gait Parameters and Walking Patterns Show the Significant Differences Between Parkinson’s Disease and Healthy Participants?
title_full_unstemmed Which Gait Parameters and Walking Patterns Show the Significant Differences Between Parkinson’s Disease and Healthy Participants?
title_sort which gait parameters and walking patterns show the significant differences between parkinson’s disease and healthy participants?
publisher MDPI AG
series Biosensors
issn 2079-6374
publishDate 2019-04-01
description This study investigated the difference in the gait of patients with Parkinson’s disease (PD), age-matched controls and young controls during three walking patterns. Experiments were conducted with 24 PD, 24 age-matched controls and 24 young controls, and four gait intervals were measured using inertial measurement units (IMU). Group differences between the mean and variance of the gait parameters (stride interval, stance interval, swing interval and double support interval) for the three groups were calculated and statistical significance was tested. The results showed that the variance in each of the four gait parameters of PD patients was significantly higher compared with the controls, irrespective of the three walking patterns. This study showed that the variance of any of the gait interval parameters obtained using IMU during any of the walking patterns could be used to differentiate between the gait of PD and control people.
topic Parkinson’s disease
gait
variance
IMU
url https://www.mdpi.com/2079-6374/9/2/59
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