Synthesis, Characterization, and Antimicrobial Activities of Coordination Compounds of Aspartic Acid

Coordination compounds of aspartic acid were synthesized in basic and acidic media, with metal ligand M : L stoichiometric ratio 1 : 2. The complexes were characterized using infrared, electronic and magnetic susceptibility measurements, and mass spectrometry. Antimicrobial activity of the compounds...

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Bibliographic Details
Main Authors: T. O. Aiyelabola, D. A. Isabirye, E. O. Akinkunmi, O. A. Ogunkunle, I. A. O. Ojo
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2016/7317015
Description
Summary:Coordination compounds of aspartic acid were synthesized in basic and acidic media, with metal ligand M : L stoichiometric ratio 1 : 2. The complexes were characterized using infrared, electronic and magnetic susceptibility measurements, and mass spectrometry. Antimicrobial activity of the compounds was determined against three Gram-positive and three Gram-negative bacteria and one fungus. The results obtained indicated that the availability of donor atoms used for coordination was a function of the pH of the solution in which the reaction was carried out. This resulted in varying geometrical structures for the complexes. The compounds exhibited a broad spectrum of activity and in some cases better activity than the standard.
ISSN:2090-9063
2090-9071