Contribution of V(H) replacement products in mouse antibody repertoire.

Contribution of V(H) replacement products in mouse antibody repertoire.

VH replacement occurs through RAG-mediated recombination between the cryptic recombination signal sequence (cRSS) near the 3' end of a rearranged VH gene and the 23-bp RSS from an upstream unrearranged VH gene. Due to the location of the cRSS, VH replacement leaves a short stretch of nucleotide...

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Bibliographic Details
Main Authors:	Lin Huang, Miles D Lange, Yangsheng Yu, Song Li, Kaihong Su, Zhixin Zhang
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2013-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3585286?pdf=render

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