Peroxynitrite induced mitochondrial biogenesis following MnSOD knockdown in normal rat kidney (NRK) cells

Peroxynitrite induced mitochondrial biogenesis following MnSOD knockdown in normal rat kidney (NRK) cells

Superoxide is widely regarded as the primary reactive oxygen species (ROS) which initiates downstream oxidative stress. Increased oxidative stress contributes, in part, to many disease conditions such as cancer, atherosclerosis, ischemia/reperfusion, diabetes, aging, and neurodegeneration. Manganes...

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Bibliographic Details
Main Authors: Akira Marine, Kimberly J. Krager, Nukhet Aykin-Burns, Lee Ann MacMillan-Crow
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Redox Biology
Subjects:
MnSOD
Peroxynitrite
siRNA
mtDNA
Respiration
Mitochondrial biogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231714000299

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