Correlation between glycemic variability and gastroesophageal reflux in adolescentswith type 1 diabetes mellitus

Aims. To estimate an impact of glycemic variability on the development of gastroesophageal reflux disease (GERD) in adolescents with type 1 diabetes mellitus (T1DM). Materials and methods. We enrolled 33 patients with T1DM aged from 12 to 17 years. 24-h pH-monitoring was performed with ?Gas- tr...

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Bibliographic Details
Main Authors: I L Alimova, S E Kostyakov
Format: Article
Language:English
Published: Endocrinology Research Centre 2013-03-01
Series:Сахарный диабет
Subjects:
Online Access:https://dia-endojournals.ru/dia/article/viewFile/3595/1771
Description
Summary:Aims. To estimate an impact of glycemic variability on the development of gastroesophageal reflux disease (GERD) in adolescents with type 1 diabetes mellitus (T1DM). Materials and methods. We enrolled 33 patients with T1DM aged from 12 to 17 years. 24-h pH-monitoring was performed with ?Gas- troskan 24? system (Istok-Sistema, Fryazino); 24-h continuous glucose monitoring utilized CGMS MMT-7310 (Medtronic Minimed, USA) with subsequent night-time analysis. Results. As compared to stable night-time glycemia controls (SD 2.0 mmol/L) showed longer period of esophageal acidification (17% [2?58]; p
ISSN:2072-0351
2072-0378