A lithium-containing biomaterial promotes chondrogenic differentiation of induced pluripotent stem cells with reducing hypertrophy

A lithium-containing biomaterial promotes chondrogenic differentiation of induced pluripotent stem cells with reducing hypertrophy

Abstract Background Induced pluripotent stem cells (iPSCs) exhibit limitless pluripotent plasticity and proliferation capability to provide an abundant cell source for tissue regenerative medicine. Thus, inducing iPSCs toward a specific differentiation direction is an important scientific question....

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Bibliographic Details
Main Authors: Yaqian Hu, Lei Chen, Yi Gao, Pengzhen Cheng, Liu Yang, Chengtie Wu, Qiang Jie
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Stem Cell Research & Therapy
Subjects:
iPSCs
Li2Ca4Si4O13 bioceramic
Chondrocytes
Online Access:http://link.springer.com/article/10.1186/s13287-020-01606-w

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