A comprehensive characterization of the cell-free transcriptome reveals tissue- and subtype-specific biomarkers for cancer detection
Cell-free RNA (cfRNA) is a promising analyte for cancer diagnosis. Here, the authors determine the baseline cell-free transcriptome in the absence of cancer and identify tissue- and subtype-specific cfRNA biomarkers in breast and lung cancer patients.
Main Authors: | Matthew H. Larson, Wenying Pan, Hyunsung John Kim, Ruth E. Mauntz, Sarah M. Stuart, Monica Pimentel, Yiqi Zhou, Per Knudsgaard, Vasiliki Demas, Alexander M. Aravanis, Arash Jamshidi |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-04-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-22444-1 |
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