OptFill: A Tool for Infeasible Cycle-Free Gapfilling of Stoichiometric Metabolic Models

Summary: Stoichiometric metabolic modeling, particularly genome-scale models (GSMs), is now an indispensable tool for systems biology. The model reconstruction process typically involves collecting information from public databases; however, incomplete systems knowledge leaves gaps in any reconstruc...

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Bibliographic Details
Main Authors: Wheaton L. Schroeder, Rajib Saha
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219305280