Macrophages-derived exosomal lncRNA LIFR-AS1 promotes osteosarcoma cell progression via miR-29a/NFIA axis

Macrophages-derived exosomal lncRNA LIFR-AS1 promotes osteosarcoma cell progression via miR-29a/NFIA axis

Abstract Background Osteosarcoma (OS) is the most common primary malignant bone tumor in young people. Tumor-associated macrophages (TAMs) have been reported to play an important role in the development of osteosarcoma. However, the detailed molecular mechanisms remain largely unknown and need to be...

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Bibliographic Details
Main Authors: Hongliang Zhang, Yiyang Yu, Jun Wang, Yu Han, Tingting Ren, Yi Huang, Chenglong Chen, Qingshan Huang, Wei Wang, Jianfang Niu, Jingbing Lou, Wei Guo
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Cancer Cell International
Subjects:
Bone tumor
Tumor-associated macrophages
Exosomal lncRNA
LIFR-AS1
Exosome
Online Access:https://doi.org/10.1186/s12935-021-01893-0

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