Alterations in TP53, cyclin D2, c-Myc, p21WAF1/CIP1 and p27KIP1 expression associated with progression in B-CLL

Alterations in TP53, cyclin D2, c-Myc, p21WAF1/CIP1 and p27KIP1 expression associated with progression in B-CLL

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B-cell chronic lymphocytic leukaemia (B-CLL) originates from B lymphocytes that may differ in the activationlevel, maturation state or cellular subgroups in peripheral blood. Tumour progression in CLL B cells seems to result in gradualaccumulation of the clone of resting B lymphocytes in the early p...

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Bibliographic Details
Main Authors: Antosz Halina, Paterski Artur, Marzec-Kotarska Barbara, Sajewicz Joanna, Dmoszyñska Anna
Format: Article
Language:English
Published: Via Medica 2010-04-01
Series:Folia Histochemica et Cytobiologica
Subjects:
B-CLL
c-Myc
TP-53
cyclin D2
p27KIP1
Online Access:http://www.fhc.viamedica.pl/darmowy_pdf.phtml?indeks=128&indeks_art=1275

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