In Vivo Models for Cholangiocarcinoma—What Can We Learn for Human Disease?

Cholangiocarcinoma (CCA) comprises a heterogeneous group of primary liver tumors. They emerge from different hepatic (progenitor) cell populations, typically via sporadic mutations. Chronic biliary inflammation, as seen in primary sclerosing cholangitis (PSC), may trigger CCA development. Although s...

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Bibliographic Details
Main Authors: Raphael Mohr, Burcin Özdirik, Jana Knorr, Alexander Wree, Münevver Demir, Frank Tacke, Christoph Roderburg
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/14/4993