Preparation of Silica Nanoparticles Loaded with Nootropics and Their In Vivo Permeation through Blood-Brain Barrier

The blood-brain barrier prevents the passage of many drugs that target the central nervous system. This paper presents the preparation and characterization of silica-based nanocarriers loaded with piracetam, pentoxifylline, and pyridoxine (drugs from the class of nootropics), which are designed to e...

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Bibliographic Details
Main Authors: Josef Jampilek, Kamil Zaruba, Michal Oravec, Martin Kunes, Petr Babula, Pavel Ulbrich, Ingrid Brezaniova, Radka Opatrilova, Jan Triska, Pavel Suchy
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/812673