Rapid MRSA detection via tandem mass spectrometry of the intact 80 kDa PBP2a resistance protein

Abstract Treatment of antibiotic-resistant infections is dependent on the detection of specific bacterial genes or proteins in clinical assays. Identification of methicillin-resistant Staphylococcus aureus (MRSA) is often accomplished through the detection of penicillin-binding protein 2a (PBP2a). W...

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Bibliographic Details
Main Authors: Jason R. Neil, Arvind Verma, Scott R. Kronewitter, William M. McGee, Christopher Mullen, Marjaana Viirtola, Annika Kotovuori, Herdis Friedrich, Johan Finell, Joni Rannisto, John E. P. Syka, James L. Stephenson
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-97844-w