Ketamine and rapid-acting antidepressants: a new era in the battle against depression and suicide [version 1; referees: 3 approved]

Therapeutic medications for the treatment of depression have serious limitations, particularly delayed onset and low rates of efficacy. However, the discovery that a single subanesthetic dose of ketamine, a glutamate NMDA receptor channel blocker, can produce a rapid (within hours) antidepressant re...

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Bibliographic Details
Main Author: Ronald S. Duman
Format: Article
Language:English
Published: F1000 Research Ltd 2018-05-01
Series:F1000Research
Online Access:https://f1000research.com/articles/7-659/v1