Chromatin Modification and Remodeling in Heart Development

Chromatin Modification and Remodeling in Heart Development

In organogenesis, cell types are specified from determined precursors as morphogenetic patterning takes place. These events are largely controlled by tissue-specific transcription factors. These transcription factors must function within the context of chromatin to activate or repress target genes....

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Main Authors: Paul Delgado-Olguín, Jun K. Takeuchi, Benoit G. Bruneau
Format: Article
Language:English
Published: Hindawi Limited 2006-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2006.315
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spelling doaj-0df7686cba8c4aa097fd7f02b347ab462020-11-25T02:19:12ZengHindawi LimitedThe Scientific World Journal1537-744X2006-01-0161851186110.1100/tsw.2006.315Chromatin Modification and Remodeling in Heart DevelopmentPaul Delgado-Olguín0Jun K. Takeuchi1Benoit G. Bruneau2Programmes in Cardiovascular Research and Developmental Biology, The Hospital for Sick Children, Toronto, ON, CanadaProgrammes in Cardiovascular Research and Developmental Biology, The Hospital for Sick Children, Toronto, ON, CanadaProgrammes in Cardiovascular Research and Developmental Biology, The Hospital for Sick Children, Toronto, ON, CanadaIn organogenesis, cell types are specified from determined precursors as morphogenetic patterning takes place. These events are largely controlled by tissue-specific transcription factors. These transcription factors must function within the context of chromatin to activate or repress target genes. Recent evidence suggests that chromatin-remodeling and -modifying factors may have tissue-specific function. Here we review the potential roles for chromatin-remodeling and -modifying proteins in the development of the mammalian heart.http://dx.doi.org/10.1100/tsw.2006.315
collection DOAJ
language English
format Article
sources DOAJ
author Paul Delgado-Olguín
Jun K. Takeuchi
Benoit G. Bruneau
spellingShingle Paul Delgado-Olguín
Jun K. Takeuchi
Benoit G. Bruneau
Chromatin Modification and Remodeling in Heart Development
The Scientific World Journal
author_facet Paul Delgado-Olguín
Jun K. Takeuchi
Benoit G. Bruneau
author_sort Paul Delgado-Olguín
title Chromatin Modification and Remodeling in Heart Development
title_short Chromatin Modification and Remodeling in Heart Development
title_full Chromatin Modification and Remodeling in Heart Development
title_fullStr Chromatin Modification and Remodeling in Heart Development
title_full_unstemmed Chromatin Modification and Remodeling in Heart Development
title_sort chromatin modification and remodeling in heart development
publisher Hindawi Limited
series The Scientific World Journal
issn 1537-744X
publishDate 2006-01-01
description In organogenesis, cell types are specified from determined precursors as morphogenetic patterning takes place. These events are largely controlled by tissue-specific transcription factors. These transcription factors must function within the context of chromatin to activate or repress target genes. Recent evidence suggests that chromatin-remodeling and -modifying factors may have tissue-specific function. Here we review the potential roles for chromatin-remodeling and -modifying proteins in the development of the mammalian heart.
url http://dx.doi.org/10.1100/tsw.2006.315
work_keys_str_mv AT pauldelgadoolguin chromatinmodificationandremodelinginheartdevelopment
AT junktakeuchi chromatinmodificationandremodelinginheartdevelopment
AT benoitgbruneau chromatinmodificationandremodelinginheartdevelopment
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