Human physiologically based pharmacokinetic model for propofol

<p>Abstract</p> <p>Background</p> <p>Propofol is widely used for both short-term anesthesia and long-term sedation. It has unusual pharmacokinetics because of its high lipid solubility. The standard approach to describing the pharmacokinetics is by a multi-compartmental...

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Bibliographic Details
Main Authors: Schnider Thomas W, Levitt David G
Format: Article
Language:English
Published: BMC 2005-04-01
Series:BMC Anesthesiology
Online Access:http://www.biomedcentral.com/1471-2253/5/4