Recent Advances in Endometrial Cancer [version 1; referees: 2 approved]

• Main Authors: Arthur-Quan Tran, Paola Gehrig
• Format: Article
• Language: English
• Published: F1000 Research Ltd 2017-01-01
• Series: F1000Research
• Subjects: Cancer Therapeutics; Gynecological Cancers; Immunopharmacology & Hematologic Pharmacology; Medical Genetics; Pharmacogenomics
• Online Access: https://f1000research.com/articles/6-81/v1

Endometrial cancer is the most common gynecologic malignancy in the United States, with yearly rates continuing to increase. Most women present with early stage disease; however, advanced disease carries a grave prognosis. As a result, novel therapies are currently under investigation for the treatment of endometrial cancer. These advances include a better understanding of the genetic basis surrounding the development of endometrial cancer, novel surgical therapies, and new molecular targets for the treatment of this disease. This review explores the literature regarding these advancements in endometrial cancer.