High-Fat Diet Alleviates Neuroinflammation and Metabolic Disorders of APP/PS1 Mice and the Intervention With Chinese Medicine

High-Fat Diet Alleviates Neuroinflammation and Metabolic Disorders of APP/PS1 Mice and the Intervention With Chinese Medicine

Alzheimer's disease (AD) is a progressive neurodegenerative disease caused by the complex interaction of multiple mechanisms. Recent studies examining the effect of high-fat diet (HFD) on the AD phenotype have demonstrated a significant influence on both inflammation and cognition. However, dif...

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Bibliographic Details
Main Authors: Xiaorui Fan, Bin Liu, Junyi Zhou, Xinru Gu, Yanyan Zhou, Yifei Yang, Feifei Guo, Xiaolu Wei, Hongjie Wang, Nan Si, Jian Yang, Baolin Bian, Haiyu Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer's disease
high fat diet
neuroinflammation
metabolism
Huanglian Jiedu decoction
gut microbiota
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.658376/full

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