Modeling the dynamics of Plasmodium vivax infection and hypnozoite reactivation in vivo.

The dynamics of Plasmodium vivax infection is characterized by reactivation of hypnozoites at varying time intervals. The relative contribution of new P. vivax infection and reactivation of dormant liver stage hypnozoites to initiation of blood stage infection is unclear. In this study, we investiga...

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Bibliographic Details
Main Authors: Adeshina I Adekunle, Mykola Pinkevych, Rose McGready, Christine Luxemburger, Lisa J White, François Nosten, Deborah Cromer, Miles P Davenport
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4364305?pdf=render