A clinical case series of COVID-19-associated acute limb ischemia: real-world situation

Abstract Background COVID-19 was a trending topic all year long in 2020. Currently, it is not only a problem for a pulmonologist since it could cause complications to many other organs, including the cardiovascular system. Recent acute COVID-19 infection state has been associated with hypercoagulati...

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Main Authors: Steven Philip Surya, Rony Marethianto Santoso
Format: Article
Language:English
Published: SpringerOpen 2021-06-01
Series:The Egyptian Heart Journal
Subjects:
Online Access:https://doi.org/10.1186/s43044-021-00187-0
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spelling doaj-0de48f7717054c8baf9c63efa091843e2021-07-04T11:34:27ZengSpringerOpenThe Egyptian Heart Journal2090-911X2021-06-017311710.1186/s43044-021-00187-0A clinical case series of COVID-19-associated acute limb ischemia: real-world situationSteven Philip Surya0Rony Marethianto Santoso1Primaya Hopsital TangerangDepartment of Cardiology and Vascular Medicine, Primaya Hospital TangerangAbstract Background COVID-19 was a trending topic all year long in 2020. Currently, it is not only a problem for a pulmonologist since it could cause complications to many other organs, including the cardiovascular system. Recent acute COVID-19 infection state has been associated with hypercoagulation and causing microthrombi called immunothrombus. Acute limb ischemia is one of the rare complications but organ-threatening. Unfortunately, unlike coronary artery disease, there is no recent guideline for cardiologists to diagnose and manage acute limb ischemia in pandemic situations Case presentation This case series presented two patients with acute limb injury (ALI)-complicating COVID-19, with chief complaints of pain at their lower extremity. The first patient was an 80-year-old woman who was just dismissed from the hospital due to COVID-19. The distal part of her toe was cyanosed, and her motoric and sensory functions were partially reduced. She was treated with oral drug therapy due to unwillingness to be hospitalized. Interestingly, she had recovered by using oral drug therapy. The second case was a 54-years-old female with several comorbidities such as obesity, type 2 diabetes mellitus, hypertension, dyslipidemia, and chronic obstructive pulmonary disease. She had cyanosed foot and weak arterial pulsation. Unfortunately, she passed away due to acute respiratory distress syndrome. Conclusion Several internal and external factors cause ALI treatment to be more challenging in the pandemic COVID-19 situation. The diagnosis and management of ALI in COVID-19 patients may not fully comply with the current guideline and are likely to be affected by local hospital regulations. Clinical follow-up might be an essential feature in treating ALI in COVID-19 patients.https://doi.org/10.1186/s43044-021-00187-0COVID-19Acute limb ischemiaImmunothrombusCase reportCOVID-19-associated coagulopathy
collection DOAJ
language English
format Article
sources DOAJ
author Steven Philip Surya
Rony Marethianto Santoso
spellingShingle Steven Philip Surya
Rony Marethianto Santoso
A clinical case series of COVID-19-associated acute limb ischemia: real-world situation
The Egyptian Heart Journal
COVID-19
Acute limb ischemia
Immunothrombus
Case report
COVID-19-associated coagulopathy
author_facet Steven Philip Surya
Rony Marethianto Santoso
author_sort Steven Philip Surya
title A clinical case series of COVID-19-associated acute limb ischemia: real-world situation
title_short A clinical case series of COVID-19-associated acute limb ischemia: real-world situation
title_full A clinical case series of COVID-19-associated acute limb ischemia: real-world situation
title_fullStr A clinical case series of COVID-19-associated acute limb ischemia: real-world situation
title_full_unstemmed A clinical case series of COVID-19-associated acute limb ischemia: real-world situation
title_sort clinical case series of covid-19-associated acute limb ischemia: real-world situation
publisher SpringerOpen
series The Egyptian Heart Journal
issn 2090-911X
publishDate 2021-06-01
description Abstract Background COVID-19 was a trending topic all year long in 2020. Currently, it is not only a problem for a pulmonologist since it could cause complications to many other organs, including the cardiovascular system. Recent acute COVID-19 infection state has been associated with hypercoagulation and causing microthrombi called immunothrombus. Acute limb ischemia is one of the rare complications but organ-threatening. Unfortunately, unlike coronary artery disease, there is no recent guideline for cardiologists to diagnose and manage acute limb ischemia in pandemic situations Case presentation This case series presented two patients with acute limb injury (ALI)-complicating COVID-19, with chief complaints of pain at their lower extremity. The first patient was an 80-year-old woman who was just dismissed from the hospital due to COVID-19. The distal part of her toe was cyanosed, and her motoric and sensory functions were partially reduced. She was treated with oral drug therapy due to unwillingness to be hospitalized. Interestingly, she had recovered by using oral drug therapy. The second case was a 54-years-old female with several comorbidities such as obesity, type 2 diabetes mellitus, hypertension, dyslipidemia, and chronic obstructive pulmonary disease. She had cyanosed foot and weak arterial pulsation. Unfortunately, she passed away due to acute respiratory distress syndrome. Conclusion Several internal and external factors cause ALI treatment to be more challenging in the pandemic COVID-19 situation. The diagnosis and management of ALI in COVID-19 patients may not fully comply with the current guideline and are likely to be affected by local hospital regulations. Clinical follow-up might be an essential feature in treating ALI in COVID-19 patients.
topic COVID-19
Acute limb ischemia
Immunothrombus
Case report
COVID-19-associated coagulopathy
url https://doi.org/10.1186/s43044-021-00187-0
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