The promise(s) of mesenchymal stem cell therapy in averting preclinical diabetes: lessons from in vivo and in vitro model systems

Abstract Obesity (Ob) poses a significant risk factor for the onset of metabolic syndrome with associated complications, wherein the Mesenchymal Stem Cell (MSC) therapy shows pre-clinical success. Here, we explore the therapeutic applications of human Placental MSCs (P-MSCs) to address Ob-associated...

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Bibliographic Details
Main Authors: Nagasuryaprasad Kotikalapudi, Samuel Joshua Pragasam Sampath, Sinha Sukesh Narayan, Bhonde Ramesh R, Harishankar Nemani, Sathish Kumar Mungamuri, Vijayalakshmi Venkatesan
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-96121-0