Trehalose Activates CRE-Dependent Transcriptional Signaling in HT22 Mouse Hippocampal Neuronal Cells: A Central Role for PKA Without cAMP Elevation
Cyclic adenosine 3′,5′monophosphate (cAMP) regulated element binding protein (CREB) is a transcription factor involved in many different signaling processes including memory storage and retrieval. The mouse hippocampal neuronal cell line HT22 is widely used as a model system for neuronal cell death...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2018-10-01
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Series: | Frontiers in Molecular Neuroscience |
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Online Access: | https://www.frontiersin.org/article/10.3389/fnmol.2018.00386/full |