Evasion of antiviral innate immunity by Theiler's virus L* protein through direct inhibition of RNase L.
Theiler's virus is a neurotropic picornavirus responsible for chronic infections of the central nervous system. The establishment of a persistent infection and the subsequent demyelinating disease triggered by the virus depend on the expression of L*, a viral accessory protein encoded by an alt...
Main Authors: | Frédéric Sorgeloos, Babal Kant Jha, Robert H Silverman, Thomas Michiels |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC3694852?pdf=render |
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