Metformin ameliorates olanzapine-induced insulin resistance via suppressing macrophage infiltration and inflammatory responses in rats

Aims: The present study aimed to investigate the possible effects of metformin on the olanzapine-induced insulin resistance in rats. Methods: Rats were randomly divided into three groups: the control (Control) group, the olanzapine (Ola) group and the olanzapine + metformin (Ola + Met) group. Rats i...

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Bibliographic Details
Main Authors: Cuilian Guo, Jinxin Liu, Huqun Li
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220311045