A role for NF-κB activity in skin hyperplasia and the development of keratoacanthomata in mice.

Previous studies have implicated NF-κB signaling in both cutaneous development and oncogenesis. However, these studies have been limited in part by the lethality that results from extreme over- or under-expression of NF-κB in available mouse models. Even cre-driven tissue specific expression of tran...

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Bibliographic Details
Main Authors: Brian Poligone, Matthew S Hayden, Luojing Chen, Alice P Pentland, Eijiro Jimi, Sankar Ghosh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3747062?pdf=render