Extrachromosomal Circular DNA: Category, Biogenesis, Recognition, and Functions
Extrachromosomal circular DNA (eccDNA), existing as double-stranded circular DNA, is derived and free from chromosomes. It is common in eukaryotes but has a strong heterogeneity in count, length, and origin. It has been demonstrated that eccDNA could function in telomere and rDNA maintenance, aging,...
Main Authors: | Xiukai Cao, Shan Wang, Ling Ge, Weibo Zhang, Jinlin Huang, Wei Sun |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-09-01
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Series: | Frontiers in Veterinary Science |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2021.693641/full |
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